ADHD medications may have potential for treating Alzheimer’s

/ Anatomy Insider, LONDON – Noradrenergic drugs, such as those used to treat ADHD (attention deficit hyperactivity disorder), depression or hypertension, can also improve some key Alzheimer’s symptoms. This is the result of an aggregate analysis of the data available online in the Journal of Neurology Neurosurgery and Psychiatry has been published (JNNP 2022; … Read more

Vitamin D in pregnancy could prevent neurodermatitis

/ Valerii Honcharuk, Southampton – A randomized trial demonstrated cholecalciferol replacement in pregnant women with proven vitamin D deficiency British Journal of Dermatology (2022; DOI: 10.1111 / bjd.21721) reduced the frequency of eczema in the first year of life. Subsequently, only a downward trend was detected. The UK Vitamin D Maternal Osteoporosis Study (MAVIDOS) … Read more

Breast cancer metastasizes mainly at night

/ Axel Kock, Zurich – Breast cancer cells are apparently postactive. The number of circulating cancer cells in the blood was in one study a Nature (2022; DOI: 10.1038 / s41586-022-04875-y) was the highest in mice and patients during the rest period. This could have implications for cancer therapy. When and why cells detach … Read more

CSF proteome signature provides candidate biomarkers for …

/ SciePro, Tübingen – Preclinical studies indicate that disease-related altered CSF proteome contains candidate biomarkers in neurodegenerative diseases. In the case of Alzheimer’s and Parkinson’s, additional diagnostic options would be desirable, for example for patient risk stratification and for monitoring the efficacy of therapeutic agents. Due to the significant genetic heterogeneity and comorbidities, such … Read more

A fluid bolus does not protect against endotracheal intubation from …

/ sudok1, BIRMINGHAM – An intravenous bolus of fluids does not appear to protect critically ill patients undergoing endotracheal intubation in the ICU from cardiovascular collapse. This is the result of a randomized study with over 1,000 patients from the USA, the results of which are published in JAMA have been published (2022; DOI: … Read more