Herbal substances prevent inflammation |

Green tea, dark chocolate, and blueberries contain polyphenols, which are secondary plant compounds. According to a study, they can prevent inflammation in older people by modifying the gut flora and stimulating bacteria to produce substances that are beneficial to health.

There is growing scientific evidence that regular dietary polyphenol intake can contribute to healthy aging. Now, a new study in the journal Molecular Nutrition and Food Research shows that polyphenols in the gut flora cause the proliferation of bacteria that produce indole-3-propionic acid (PAH). IPA has anti-inflammatory and other health-promoting properties that help prevent some age-related diseases.

After eight weeks of switching to a polyphenol-rich diet with lots of green tea, dark chocolate, and fruits like apples, pomegranates, and blueberries, 51 people aged 60 and over experienced a significant increase in PAHs in their blood, accompanied by a reduction in inflammation levels. Such a change in diet could therefore be helpful in preventing chronic diseases in the elderly that affect their quality of life.

Surprisingly, these effects were absent in people with kidney disease, which could be related to altered gut flora. Even at the start of the study, these people already had lower IPA levels. ‘The findings may be clinically relevant as low levels of PAH have been associated with rapid decline in kidney function and chronic kidney disease,’ said Professor Cristina Andrés-Lacueva of the University of Barcelona.

Those: DOI 10.1002 / mnfr. 202100349

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