Early prediction of the risk of cardiovascular disease
A biomedical microdevice under development aims at changes in the blood identify which ones occur before it becomes one heart attack or stroke he arrives. Such an anticipated forecast could help save millions of lives around the world every year.
In a recent study involving experts from University of Sydney a method has already been devised minimal changes in platelets to identify which one can lead to heart attacks and strokes.
The results of the research work can be read in the English-language journal “Analyst”.
Many deaths from cardiovascular disease
In Germany, according to the Robert Koch Institute (RKI) approx 40 percent of all deaths associated with cardiovascular disease. Coronary heart disease is particularly common heart attacks And strokes.
Heart attacks and strokes often occur without warning
Heart attacks and strokes occur frequently standing without warningas it often happens blood clot explain the researchers involved in the new study.
But long before a heart attack or stroke occurs, be already small changes in the blood detectable. For example, blood flow is often disturbed, which leads to increased blood clotting and inflammation, which then causes the block blood vessels being able.
The device only requires a blood draw
The newly developed micro device aims at subtle platelet changes identify even before a heart attack or stroke occurs. The device could use a simple pin prick test to do this blood sample taken by a person’s finger, the team reports.
Then the sample taken will be on the clotting of platelets and inflammatory reactions of white blood cells. This information could then be evaluated immediately by an external operating system.
Test those at risk every day
“The device would work in such a way that a person at risk, eg. B. someone with heart problems, use it daily. Using a prick test, the device would monitor their blood and alert them of potentially dangerous changes‘explains the author of the study Dr. Arnold Lining Ju of the University of Sydney in a recent press release.
If within such a test a critical change identified be, interested people should further monitoring visit to the hospitaladds the doctor.
Better understanding of the causes of blood clots
“Our hope is that this device will shed some light on why and how blood clots form and that, if successful, it can someday be used in a range of healthcare scenarios.“, underlines the author of the study Professor Shaun Jackson.
Until now, it has been difficult to predict when a heart attack or stroke could occur. Therefore, these diseases appear to occur randomly, which sometimes happens without physical symptoms, explains the study’s author Laura Moldova.
They actually do occur in such a case though small physical changes in the blood of those affected and that the new device is capable of doing just that to monitor microscopic changes extremely closelyLike this Moldovan.
The next step is artificial intelligence (AI) can be used to understand the blood counts of individuals and the like to create a customized blood profile, the team reports. (how)
Information on the author and source
This text corresponds to the specifications of the specialist medical literature, medical guidelines and current studies and has been verified by medical professionals.
- Lining Arnold Ju, Sabine Kossmann, Yunduo Charles Zhao, Laura Moldovan, Yingqi Zhang, et al .: Post microfluidic method for three-dimensional modeling of platelet-leukocyte interactions; in: Analyst (veröffentlicht 18.02.2022), Analyst
- University of Sydney: the micro-device could detect the first signs of heart attack or stroke (veröffentlicht 20.06.2022), University of Sydney
- Rober Koch Institute: Cardiovascular Diseases (accessed June 20, 2022), RKI
This article contains general advice only and is not to be used for self-diagnosis or treatment. It cannot replace a visit to the doctor.