Better understanding of the risk of developing dementia
When people at the same time Type 2 diabetes and heart disease she give, doubled this you risk of developing dementia. Preventing diabetes and cardiovascular disease could also help reduce the risk of dementia.
In a new expert study by Karolinska Institute in Sweden the combined effect of cardiometabolic diseases on the risk of developing dementia was studied. The findings were published in the Alzheimer’s & Dementia journal.
Data from 2,500 participants were evaluated
For the new research work Daten aus der Swedish National Study on Aging and Care Used. Overall, the data from 2,500 healthy people over the age of 60 who did not suffer from dementia at the start of the study.
At the beginning of the study, the onset of cardiometabolic diseases was assessed Medical records and clinical examinations determined. The participants were then for a period of under medical supervision for twelve years.
Additionally, the participants had to take cognitive tests to do so Changes in cognitive abilities and the development of dementia observed, according to experts.
How does dementia develop?
Dementia develops very slowly and takes decades. The disease first manifests itself as gradual cognitive declinewhich can only be determined in cognitive tests.
Poor memory as a sign of dementia
According to the team, the next step is a cognitive impairment on, in which the affected people themselves realize they are under poor memory they suffer but are still able to take care of themselves. Eventually, full-fledged dementia develops and the patient can no longer cope with everyday life independently.
Cardiometabolic diseases risk factors for dementia
The so-called cardiometabolic diseases (Type 2 diabetes, ischemic heart disease, congestive heart failure, atrial fibrillation and stroke) are considered the most important risk factors for dementiathe researchers report.
Yet “Few studies have examined how the coexistence of many of these diseases affects the risk of dementia, and that’s exactly what we wanted to investigate in our study.‘explains the author of the study Abigail Dove in a press release.
Double risk of dementia identified
Data analysis showed that the presence of more than a cardiometabolic disease the rate of cognitive decline greatly accelerated. This also led to the risk of developing dementia doubling, the researchers report.
That The risk increases with the number of diseases his specific combinations of diseases seemed to increase the risk of dementia particularly strongly. “In our study, the combinations diabetes / heart disease and diabetes / heart disease / stroke were the most damaging to cognitive function.‘reports Colomba.
Experts add that, however, people only do that a cardiometabolic disease I had, no significantly higher risk of dementia exposed.
This can prevent dementia from developing
“This is good news. The study shows that the risk only increases when someone has at least two of these diseases“, points out Dove. Dementia can be prevented by preventing the development of a second disease.
Prevention already in middle age
The study also found that the correlation between cardiometabolic disease and dementia risk was stronger in participants younger than 78.
“We should therefore focus on the prevention of cardiometabolic disease from middle age, as the risk of cognitive impairment and dementia appears to be higher in those who develop cardiometabolic disease earlier in life.“, Like this Dove.
In the future, the team hopes to learn more about the mechanism behind this association. This is what the effects are supposed to do genetic factors examined and brain imaging used to determine how cardiometabolic diseases damage the brain being able. (how)
Information on the author and source
This text corresponds to the specifications of the specialist medical literature, medical guidelines and current studies and has been verified by medical professionals.
- Abigail Dove, Anna Marseglia, Ying Shang, Giulia Grande, Davide Liborio Vetrano, et al .: Cardiometabolic multimorbidity accelerates cognitive decline and progression of dementia; in: Alzheimer’s and dementia (veröffentlicht 16.06.2022), Alzheimer’s and dementia
- Karolinska Institutet: Diabetes and cardiovascular disease increase the risk of dementia (published on 16.06.2022), Karolinska Institutet
This article contains general advice only and is not to be used for self-diagnosis or treatment. It cannot replace a visit to the doctor.